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Simufilam dihydrochloride
CAS No. 2480226-06-8
Simufilam dihydrochloride ( PTI-125 dihydrochloride )
产品货号. M24133 CAS No. 2480226-06-8
Simufilam dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer's disease.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1239 | 有现货 |
|
| 10MG | ￥1968 | 有现货 |
|
| 25MG | ￥4172 | 有现货 |
|
| 50MG | ￥5419 | 有现货 |
|
| 100MG | ￥7055 | 有现货 |
|
| 200MG | ￥9315 | 有现货 |
|
| 500MG | ￥13608 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Simufilam dihydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Simufilam dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer's disease.
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产品描述Simufilam dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer's disease. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
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同义词PTI-125 dihydrochloride
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通路Others
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靶点Other Targets
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受体filamin A (FLNA)
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研究领域——
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适应症——
化学信息
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CAS Number2480226-06-8
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分子量332.3
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分子式C15H23Cl2N3O
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纯度>98% (HPLC)
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溶解度——
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SMILES[H]Cl.O=C1N(CC2=CC=CC=C2)C3(CCN(C)CC3)NC1.[H]Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Wang HY, et al. PTI-125 binds and reverses an altered conformation of filamin A to reduce Alzheimer's disease pathogenesis. Neurobiol Aging. 2017;55:99-114.
产品手册
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